Synthesis of some quinoline intermediates under phase transfer catalyst VETRIVEL NADARAJ1* and SENNIAPPAN THAMARAI SELVI2
نویسندگان
چکیده
The microwave synthesis of quinoline alkaloid 4-methoxyquinolin-2(1H)-one 3a and its analogues 3b-e was achieved in 8-11 minutes by methoxydechlorinated of 4-chloroquinolin-2(1H)ones 2a-e using TBAB as phase transfer catalyst. The starting compound obtained by selective decholorination of 1a-e by sodium acetate/acetic acid and the structure of synthesized compound has been established by IR, 1H-NMR and Mass spectral data.
منابع مشابه
An Effective Green Procedure for the Synthesis of Phenacyl Derivatives Catalyzed by Silica-bound 3-{2-[Poly(ethylene glycol)]ethyl}-substituted 1-Methyl-1H-imidazol-3-ium Bromide as a Recyclable Phase Transfer Catalyst under Aqueous Media
The use of a recyclable phase transfer catalyst, SiO2-PEG-ImBr, is demonstrated in a simple and highly efficient synthesis of phenacyl derivatives by nucleophilic substitution reaction of phenacyl halides with different anions in water. Advantages of this system are easy work-up, moderate to good yields, and recyclable catalyst. The catalyst can be recycled and reused several times with no loss...
متن کاملSynthesis of 1-(isopentyloxy)-4-nitrobenzene under ultrasound assisted liquid-liquid phase-transfer catalysis
In this paper, we report the reaction of isoamyl alcohol and 1-chloro-4-nitrobenzene was carried out in a batch reactor under aqueous-organic biphasic conditions using the techniques like phase transfer catalysis and ultrasound irradiation. Tetrabutylammonium bromide (TBAB) was employed as the phase transfer catalyst. The reaction is greatly enhanced by adding a small quantity of phase-transfer...
متن کاملH3PW12O40 as an efficient catalyst for one-pot- tricomponent synthesis of chromeno[4,3-b]quinolones under microwave irradiation
Some Chromeno[4,3-b]quinoline derivatives were synthesized in a tricomponents one-pot reaction of 1,3-cyclohexadione arylaldehydes and 4-aminocoumarin under Microwave irradiation in the solventless system by using a heteropolyacid catalyst ,H3[PW12O40] in 80-95% yields and high rates. The shorter reaction times, one-pot, good yields, simple work-up procedure and environmentally friendly conditi...
متن کاملPorous Acidic Catalyst, Functionalized with Imidazole Ionic Liquid ([SBA-Im]HSO4) as a Novel Phase Transfer Catalyst for The Aqueous Synthesis of Benzyl Thiocyanates and Azides
In the present study, application of porous acidic catalyst functionalized with an imidazoleionic liquid ([SBA-Im]HSO4) as a phase transfer catalyst for the facile preparation of benzylthiocyanates and azides in water has been described. The catalyst has been characterized byFourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), transmissionelectron microscopy (TEM...
متن کاملPhase-transfer catalysis for synthesis of ethyl 2-(4-nitrophenoxy)acetate under sonication- kinetic aspects
Ultrasound assisted phase-transfer catalyzed preparation of ethyl 2-(4-nitrophenoxy)acetate from the corresponding p-nitrophenol and ethyl 2-bromoacetate using the mild solid base, anhydrous potassium carbonate, under very mild conditions is reported. The solid-liquid reactions were performed in a batch reactor equipped with reflux condenser, and ultrasonic irradiations were introduced using an...
متن کامل